PAAF1 antibody

Catalog No. ABIN7117878

This anti-PAAF1 antibody is a Rabbit Polyclonal antibody detecting PAAF1 in WB, IHC and ELISA. Suitable for Human and Mouse.

Quick Overview for PAAF1 antibody (ABIN7117878)

Target: PAAF1 (Proteasomal ATPase-Associated Factor 1 (PAAF1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAAF1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-PAAF1 Antibody

Purpose: PAAF1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: proteasomal ATPase-associated factor 1

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for PAAF1

Target: PAAF1 (Proteasomal ATPase-Associated Factor 1 (PAAF1))

Alternative Name: PAAF1

Background:

Synonyms: Proteasomal ATPase-associated factor 1|Protein G-16|WD repeat-containing protein 71|PAAF1|WDR71

Background: Inhibits proteasome 26S assembly and proteolytic activity by impairing the association of the 19S regulatory complex with the 20S core. In case of HIV-1 infection, recruited by viral Tat to the HIV-1 promoter, where it promotes the recruitment of 19S regulatory complex through dissociation of the proteasome 26S. This presumably promotes provirus transcription efficiency. Protects SUPT6H from proteasomal degradation.

Molecular Weight: 30 kDa

Gene ID: 80227

UniProt: Q9BRP4